Vayuna Therapeutics

Welcome to Vayuna Therapeutics

Vayuna Therapeutics is developing precision medications derived from nature's most potent plants to target treatment-resistant cancers within genomically defined patient populations

FIRST-IN-CLASS

Next-Generation Precision

ADCs and Parenteral Formulations with V-001
for EGFR High
& Treatment-Resistant Cancers

THE PROBLEM

Treatment Resistance in Cancer

Limited effective therapies for treatment-resistant solid tumors.

“EGFR High” expression occurs in 30–45% of breast cancers and up to 80% of solid tumors, while PIK3CA mutations appear in 30–40% of breast cancers and 10–15% of all cancers—driving PI3K overactivation and treatment resistance across tumor types.

Existing treatments are imprecise, resulting in suboptimal outcomes and significant toxicity.

the solution

Superior Efficacy

V-001 outperforms standards of care in NCI-60 screen, targeting PIK3CA-mutated and resistant cancers

EGFR/HER-2 directed ADCs

Precision delivery of V-001 payload for enhanced therapeutic effect.

Parenteral Formulations:

Systemic treatment for advanced & metastatic PIK3CA-mutated cancers.

Biomarker-Driven

Precision targeting for better outcomes, reduced toxicity and personalized care.

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